Research by members of the International Society for the Study of Human Growth and Clinical Auxology
Age at menarche and chemical exposure
Lawrence M. Schell. ABSTRACT (partial): Context: Humans are now exposed to a multitude of chemicals throughout the life course, some of which may affect growth and development owing to their endocrine-like activity.
From growth charts to growth status: How concepts of optimal growth and tempo influence the interpretation of growth measurements
Babette S. Zemel. ABSTRACT (partial): Growth measurements are largely uninterpretable without comparison to a growth chart. Consequently, the characteristics of a growth chart become an integral component of the interpretation of growth measurements. The concepts of optimal growth and tempo are well recognised by auxologists, yet their implications for interpretation of growth measurements remain problematic.
Guideline for referring short or tall children in preventive child health care
P. van Dommelen. ABSTRACT (partial): Aim: To develop a guideline for preventive child healthcare professionals in order to improve early detection of pathological disorders associated with short stature (or growth faltering) or tall stature (or accelerated growth).
Smoothing reference centile curves: The LMS method and penalized likelihood
TJ Cole. ABSTRACT (partial): Reference centile curves show the distribution of a measurement as it changes according to some covariate, often age. The LMS method summarizes the changing distribution by three curves representing the median, coefficient of variation and skewness, the latter expressed as a Box-Cox power.
Establishing a standard definition for child overweight and obesity worldwide: International survey
TJ Cole. ABSTRACT (partial): Objective: To develop an internationally acceptable definition of child overweight and obesity, specifying the measurement, the reference population, and the age and sex specific cut off points.
SITAR—a useful instrument for growth curve analysis
TJ Cole. ABSTRACT (partial): Background: Growth curve analysis is a statistical issue in life course epidemi- ology. Height in puberty involves a growth spurt, the timing and intensity of which varies between individuals. Such data can be summarized with individual Preece–Baines (PB) curves, and their five parameters then related to earlier exposures or later outcomes. But it involves fitting many curves
Sample size and sample composition for constructing growth reference centiles
TJ Cole. ABSTRACT (partial): Growth reference centile charts are widely used in child health to assess weight, height and other age-varying measure- ments. The centiles are easy to construct from reference data, using the LMS method or GAMLSS (Generalised Additive Models for Location Scale and Shape). However, there is as yet no clear guidance on how to design such studies, and in particular how many reference data to collect, and this has led to study sizes varying widely.